ABSTRACT
Objective To explore the clinical effects of diabetic nephropathy treated with enalapril and Yinxingdamo injection. Methods 80 patients were randomly recruited into a control group and a treatment group. The control group was treated with enalapril, and the treatment group was treated with Yinxingdamo injection on the basis of the control group. Results Comparing with the control group, the treatment group could be seen a obvious decrease of 24h UAE, BUN and Cr(P<0.01). Conclusion The therapeutic effects of combined using enalapril and Yinxingdamo injection is better than only using enalapril in treating diabetic nephropathy.
ABSTRACT
Objective To investigate the clinical significance of the plasma adrenomedullin(ADM) and endothelin(ET-1) concentrations in patients with serious injuries complicated by hemorrhagic shock.Method Plasma ADM and ET-1 concentrations were measured by radioimmunoassay in 38 hemorrhagic shock patients(A group)and 36 non-hemorrhagic shock patients(B group)among 74 serious injury patients in the early stage and 30 age-sexmatched healthy(C group) control subjects.Results Plasma ADM and ET-1 concentrations in B group and A group,including mild(A_1 group),middle(A_2 group) and serious(A_3 group) hemorrhagic shock patients were significantly higher than those of C group.The plasma ADM and ET-1levels were greatly higher in A group than in B group.Their levels in A_1,A_2 and A_3 groups were progressively increased.There were statistical differences between A_1 and A_2 group,A_1 and A_3 group,A_2 and A_3 group respectively.There were similar increases of the plasma ET-1/ADM ratio in A group,and the ratios in A_1,A_2 and A_3 group were progressively increased also.There were positive correlations between increased plasma ADM levels and the increased plasma ET-1 levels in both A group and B group patients(r=0.492,0.438,P